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Laboratorio di Immunologia cellulare
Pubblicazioni relative all’attività del gruppo
- Borrello MG, Alberti L, Fischer A, Degl'innocenti D, Ferrario C, Gariboldi M, Marchesi F,
Allavena P, Greco, Mantovani A, Pierotti MA Induction of a proinflammatory program in normal human
thyrocytes by the RET/PTC1 oncogene. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14825-30
- Sica A, Schioppa T, Mantovani A, Allavena P. Tumour-associated macrophages are a distinct M2
polarised population promoting tumour progression: Potential targets of anti-cancer therapy. Eur J
Cancer. 2006 Apr;42(6):717-27
- Bailey C, Negus R, Morris A, Ziprin P, Goldin R, Allavena P, Peck D, Darzi A. Chemokine
expression is associated with the accumulation of tumour associated macrophages (TAMs) and
progression in human colorectal cancer. Clin Exp Metastasis. 2007 ;24(2):121-30
- Mantovani A, Marchesi F, Porta C, Sica A, Allavena P. Inflammation and cancer: breast cancer as
a prototype. Breast. 2007 Dec;16 Suppl 2:S27-33. Epub 2007 Aug 30.
- Sica A, Rubino L, Mancino A, Larghi P, Porta C, Rimoldi M, Solinas G, Locati M, Allavena P,
Mantovani A. Targeting tumour-associated macrophages. Expert Opin Ther Targets. 2007
Sep;11(9):1219-29
- Assi F, Fruscio R, Bonardi C, Ghidini A, Allavena P, Mantovani A, Locatelli A. Pentraxin 3 in
plasma and vaginal fluid in women with preterm delivery. BJOG. 2007 Feb;114(2):143-7
- Allavena P, Sica A, Garlanda C, Mantovani A. The Yin-Yang of tumor-associated macrophages in
neoplastic progression and immune surveillance. Immunol Rev. 2008 Apr;222:155-61.
- Allavena P, Garlanda C, Borrello MG, Sica A, Mantovani A. Pathways connecting inflammation and
cancer. Curr Opin Genet Dev. 2008 Mar 4; 18:1–8
- Allavena P, Sica A, Solinas G, Porta C, Mantovani A. The inflammatory micro-environment in
tumor progression: The role of tumor-associated macrophages. Crit Rev Oncol Hematol. 2008
Apr;66(1):1-9.
- Sica A., Allavena P., Mantovani A. Cancer Related Inflammation: the macrophage Connection.
Cancer Letters. 2008 In press
- Alberto Mantovani, Paola Allavena, Antonio Sica and Frances Balkwill. Inflammation and
Cancer : the Dark Side of the Force. Nature, 2008 in Press
- Marchesi F., Piemonti L., Fedele G., Destro A., Roncalli M., Albarello L., Dogliosi C., Anselmo
A., Doni A., Bianchi P., Laghi L., Malesi A., Cervo L., Maltosio ML., Reni M., Zerbi A., Di Carlo
V., Mantovani A., Allavena P. The chemokine receptor CX3CR1 is involved in the neural tropism
and malignant behaviour of ductal pancreatic adenocarcinoma. Submitted.
Pubblicazioni selezionate (2002-2008) - dr.ssa
Paola Allavena
- Allavena P, Sica A, Garlanda C, Mantovani A. The Yin-Yang of tumor-associated macrophages in
neoplastic progression and immune surveillance. Immunol Rev. 2008 Apr;222:155-61.
- Alberto Mantovani, Paola Allavena, Antonio Sica and Frances Balkwill. Inflammation and
Cancer : the Dark Side of the Force. Nature, 2008 in Press
- Borrello MG, Alberti L, Fischer A, Degl'innocenti D, Ferrario C, Gariboldi M, Marchesi F,
Allavena P, Greco A, Collini P, Pilotti S, Cassinelli G, Bressan P, Fugazzola L, Mantovani A,
Pierotti MA. Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1
oncogene. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14825-30.
- Rimoldi M, Chieppa M, Salucci V, Avogadri F, Sonzogni A, Sampietro GM, Nespoli A, Viale G,
Allavena P, Rescigno M. Intestinal immune homeostasis is regulated by the crosstalk between
epithelial cells and dendritic cells. Nat Immunol. 2005 May;6(5):507-14. Epub 2005 Apr 10.
- Allavena P, Signorelli M, Chieppa M, Erba E, Bianchi G, Marchesi F, Olimpio CO, Bonardi C,
Garbi A, Lissoni A, de Braud F, Jimeno J, D'Incalci M. Anti-inflammatory properties of the
novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine
production. Cancer Res. 2005 Apr 1;65(7):2964-71.
- Sordi V, Malosio ML, Marchesi F, Mercalli A, Melzi R, Giordano T, Belmonte N, Ferrari G, Leone
BE, Bertuzzi F, Zerbini G, Allavena P, Bonifacio E, Piemonti L. Bone marrow mesenchymal stem cells
express a restricted set of functionally active chemokine receptors capable of promoting migration
to pancreatic islets. Blood. 2005 Jul 15;106(2):419-27. Epub 2005 Mar 22.
- Marchesi F, Monti P, Leone BE, Zerbi A, Vecchi A, Piemonti L, Mantovani A, Allavena P.
Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells
expressing functional CXCR4. Cancer Res. 2004 Nov 15;64(22):8420-7.
- Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse
forms of macrophage activation and polarization. Trends Immunol. 2004 Dec;25(12):677-86.
Review.
- Perrier P, Martinez FO, Locati M, Bianchi G, Nebuloni M, Vago G, Bazzoni F, Sozzani S, Allavena
P, Mantovani A. Distinct transcriptional programs activated by interleukin-10 with or without
lipopolysaccharide in dendritic cells: induction of the B cell-activating chemokine, CXC chemokine
ligand 13. J Immunol. 2004 Jun 1;172(11):7031-42.
- Monti P, Leone BE, Marchesi F, Balzano G, Zerbi A, Scaltrini F, Pasquali C, Calori G, Pessi F,
Sperti C, Di Carlo V, Allavena P, Piemonti L. The CC chemokine MCP-1/CCL2 in pancreatic cancer
progression: regulation of expression and potential mechanisms of antimalignant activity. Cancer
Res. 2003 Nov 1;63(21):7451-61.
- Chieppa M, Bianchi G, Doni A, Del Prete A, Sironi M, Laskarin G, Monti P, Piemonti L, Biondi A,
Mantovani A, Introna M, Allavena P. Cross-linking of the mannose receptor on monocyte-derived
dendritic cells activates an anti-inflammatory immunosuppressive program. J Immunol. 2003 Nov
1;171(9):4552-60.
- Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated
macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 2002
Nov;23(11):549-55. Review.
- Mantovani A, Locati M, Vecchi A, Sozzani S, Allavena P. Decoy receptors: a strategy to regulate
inflammatory cytokines and chemokines. Trends Immunol. 2001 Jun;22(6):328-36. Review.
- Fraticelli P, Sironi M, Bianchi G, D'Ambrosio D, Albanesi C, Stoppacciaro A,Chieppa M, Allavena
P, Ruco L, Girolomoni G, Sinigaglia F, Vecchi A, Mantovani A. Fractalkine (CX3CL1) as an
amplification circuit of polarized Th1 responses. J Clin Invest. 2001 May;107(9):1173-81.
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D'Amico G, Frascaroli G, Bianchi G, Transidico P, Doni A, Vecchi A, Sozzani S, Allavena P,
Mantovani A. Uncoupling of inflammatory chemokine receptors by IL-10: generation of
functional decoys. Nat Immunol. 2000 Nov;1(5):387-91.
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